CCG 2046

Names

[ CAS No. ]:
13017-69-1

[ Name ]:
CCG 2046

[Synonym ]:
1,1,2,2-tetracyano-3-methyl-3-propylcyclopropane
3-Methyl-3-propyl-1,1,2,2-tetracyan-cyclopropan

Biological Activity

[Description]:

CCG-2046 is a RGS4 inhibitor with an IC50 of 4.3 μM against RGS4-Gαo interaction signal[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> GPCR/G Protein >> RGS Protein

[Target]

RGS4:4.3 μM (IC50)

[References]

[1]. Roman DL, et al. Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay. Mol Pharmacol. 2007 Jan;71(1):169-75.

Chemical & Physical Properties

[ Density]:
1.17g/cm3

[ Boiling Point ]:
467.4ºC at 760mmHg

[ Molecular Formula ]:
C₁₁H₁₀N₄

[ Molecular Weight ]:
198.22400

[ Flash Point ]:
240.1ºC

[ Exact Mass ]:
198.09100

[ PSA ]:
95.16000

[ LogP ]:
1.87352

[ Vapour Pressure ]:
6.52E-09mmHg at 25°C

[ Index of Refraction ]:
1.515

Safety Information

[ HS Code ]:
2926909090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%