kapurimycin A3

Names

[ Name ]:
kapurimycin A3

[Synonym ]:
Kapurimycin A3
4H-Anthra(1,2-b)pyran-5-acetic acid,8-(acetyloxy)-8,9,10,11-tetraahydro-12-hydroxy-2-(2-methyl-3-(1-propenyl)oxiranyl)-4,11-dioxo

Biological Activity

[Description]:

Kapurimycin A3 is an antitumor and antibacterial antibiotic. Kapurimycin A3 has DNA binding and breakage activity. Kapurimycin A3 can be isolated from Streptomyces[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Hara M, et al. Covalent modification and single-strand scission of DNA by a new antitumor antibiotic kapurimycin A3. Biochemistry. 1990 Nov 20;29(46):10449-55.

[2]. PRODUCING ORGANISM, et al. THE KAPURIMYCINS, NEW ANTITUMOR ANTIBIOTICS PRODUCED BY STREPTOMYCES. The Journal of Antibiotics. 1990. 43 (12), p. 1513-1518

Chemical & Physical Properties

[ Density]:
1.49g/cm3

[ Boiling Point ]:
736.5ºC at 760mmHg

[ Molecular Formula ]:
C₂₇H₂₄O₉

[ Molecular Weight ]:
492.47400

[ Flash Point ]:
250.4ºC

[ Exact Mass ]:
492.14200

[ PSA ]:
143.64000

[ LogP ]:
4.04970

[ Vapour Pressure ]:
8.99E-23mmHg at 25°C

[ Index of Refraction ]:
1.682

Related Compounds

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