5’-O-(4,4-Dimethoxytrityl)-2’-O-methyl inosine

Names

[ Name ]:
5’-O-(4,4-Dimethoxytrityl)-2’-O-methyl inosine

[Synonym ]:
5'-O-DMT-2'-O-methylinosine

Biological Activity

[Description]:

5’-O-(4,4-Dimethoxytrityl)-2’-O-methyl inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₂H₃₂N₄O₇

[ Molecular Weight ]:
584.62

[ Exact Mass ]:
584.22700

[ PSA ]:
129.95000

[ LogP ]:
3.41880

5’-O-(4,4-Dimethoxytrityl)-2’-O-methyl inosine

Names

Biological Activity

Chemical & Physical Properties

Related Compounds