Rosuvastatin D3 Sodium

Names

[ CAS No. ]:
1279031-70-7

[ Name ]:
Rosuvastatin D3 Sodium

[Synonym ]:
(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl-d3)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Monosodium Salt
Sodium Rosuvastatin-d3
(3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methanesulfonyl-d3)methylamino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic Acid Sodium Salt
[S-[R*,S*-(E)]]-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl-d3)amino]-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic Acid Monosodium Salt
sodium (3R,5S,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-(trichloromethyl)methylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate
Rosuvastatin (D3 Sodium)

Biological Activity

[Description]:

Rosuvastatin D3 Sodium is deuterium labeled Rosuvastatin, which is a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> HMG-CoA Reductase (HMGCR)
Research Areas >> Others

[Related Small Molecules]

Rosuvastatin Calcium | Fluvastatin Sodium | Pravastatin (sodium) | Mevastatin | Nicodicosapent | Clinofibrate | SR-12813 | 3-hydroxy-3-methylglutaric acid | Lovastatin Diol Lactone

Chemical & Physical Properties

[ Melting Point ]:
>76°C (分解)

[ Molecular Formula ]:
C22H24D3FN3NaO6S

[ Molecular Weight ]:
506.53800

[ Exact Mass ]:
506.16900

[ PSA ]:
152.13000

[ LogP ]:
2.14780

[ Storage condition ]:
2-8℃

Related Compounds