(Rac)-3′-Hydroxy simvastatin

Names

[ Name ]:
(Rac)-3′-Hydroxy simvastatin

Biological Activity

[Description]:

(Rac)-3′-Hydroxy simvastatin is a metabolite of Simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM[1][2].

[Related Catalog]:

Research Areas >> Others

[References]

[1]. Slater, E.E., et al. Mechanism of action and biological profile of HMG CoA reductase inhibitors. A new therapeutic alternative. Drugs, 1988. 36 Suppl 3: p. 72-82.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₃₈O₆

[ Molecular Weight ]:
434.56600

[ Exact Mass ]:
434.26700

[ PSA ]:
93.06000

[ LogP ]:
3.55640

[ Index of Refraction ]:
1.542

Related Compounds

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