Insulin from porcine pancreas

Names

[ CAS No. ]:
12584-58-6

[ Name ]:
Insulin from porcine pancreas

[Synonym ]:
MFCD00131380
EINECS 235-703-3
Insulin (human)
Insulin

Biological Activity

[Description]:

Insulin (swine) is a porcine-derived insulin used in diabetes research[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Insulin Receptor

[References]

[1]. Z J Zhang, et al. Suppression of diabetes in nonobese diabetic mice by oral administration of porcine insulin. Proc Natl Acad Sci U S A. 1991 Nov 15;88(22):10252-6.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅₆H₃₈₁N₆₅O₇₆S₆

[ Molecular Weight ]:
5800 (Approximately)

[ Appearance of Characters ]:
powder

[ Storage condition ]:
−20°C

[ Water Solubility ]:
It can be solubilized in dilute acetic or hydrochloric acid, pH 2-3.

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
T+

[ Safety Phrases ]:
S22;S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
NM8895000

Articles

High-resolution separation of peptides by sodium dodecyl sulfate-polyacrylamide gel "focusing".

Electrophoresis 29 , 1749-52, (2008)

As a follow-up of our previous report (Anal. Chem. 2007, 79, 821-827) on analytical SDS-PAGE focusing, a refinement of the method for separation of peptides in the small to medium M(r) range (0.5-10 k...

Hormonal regulation of postnatal chicken preadipocyte differentiation in vitro.

Comp. Biochem. Physiol. B Biochem. Mol. Biol. 136(2) , 245-53, (2003)

This study was designed to develop a culture system from the stromal-vascular fraction of chicken adipose tissue that can be used to characterize hormones that promote preadipocyte differentiation. Ab...

Influence of polymers ratio on insulin-loaded nanoparticles based on poly-epsilon-caprolactone and Eudragit RS for oral administration.

Drug Deliv. 16(8) , 430-6, (2009)

Nanoparticles loaded with two different commercial insulins (Actrapid, Novorapid and based on different blends of a biodegradable polyester (poly-epsilon-caprolactone) and a polycationic non-biodegrad...