carbendazim d3

Names

[ CAS No. ]:
1255507-88-0

[ Name ]:
carbendazim d3

[Synonym ]:
Carbendazim-d3
Methyl-d3 2-benzimidazolecarbamate

Biological Activity

[Description]:

Carbendazimb-d3 is the deuterium labeled Ofloxacin. Ofloxacin (Hoe-280) is a fluoroquinolone whose primary mechanism of action is inhibition of bacterial DNA gyrase.

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Chemical & Physical Properties

[ Molecular Formula ]:
C9H6D3N3O2

[ Molecular Weight ]:
194.21

[ Exact Mass ]:
194.08800

[ PSA ]:
67.01000

[ LogP ]:
1.81420

Safety Information

[ Symbol ]:

GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H340-H360FD-H410

[ Precautionary Statements ]:
P201-P273-P308 + P313-P501

[ Hazard Codes ]:
T,N

[ Risk Phrases ]:
46-60-61-50/53

[ Safety Phrases ]:
53-45-60-61

[ RIDADR ]:
UN 3077 9 / PGIII

Related Compounds