(2S,3R)-Voruciclib

Names

[ CAS No. ]:
1253731-24-6

[ Name ]:
(2S,3R)-Voruciclib

Biological Activity

[Description]:

(2S,3R)-Voruciclib is the (2S,3R)-enantiomer of Voruciclib. (2S,3R)-Voruciclib is an orally active CDK inhibitor[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> CDK

[Target]

CDK[1]

[In Vitro]

(2S,3R)-Voruciclib (Compound B, formula I) is used in combination with a compound capable of inhibiting EGFR kinase activity and Gemcitabine to treat pancreatic cancer[1].

[References]

[1]. Veena Agarwal, et al. A synergistic pharmaceutical combination for the treatment of pancreatic cancer. WO2012123889A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₁₉ClF₃NO₅

[ Molecular Weight ]:
469.84

(2S,3R)-Voruciclib

Names

Biological Activity

Chemical & Physical Properties

Related Compounds