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Thymolphthalein

Names

[ CAS No. ]:
125-20-2

[ Name ]:
Thymolphthalein

[Synonym ]:
Thymolphthalein
MFCD00005909
3,3-Bis[4-hydroxy-2-methyl-5-(1-methylethyl)phenyl]-1(3H)-isobenzofuranone
3,3-Bis(4-hydroxy-5-isopropyl-2-methylphenyl)-2-benzofuran-1(3H)-one
TCMDC-123951
1(3H)-Isobenzofuranone, 3,3-bis[4-hydroxy-2-methyl-5-(1-methylethyl)phenyl]-
3,3-bis(4-hydroxy-2-methyl-5-propan-2-ylphenyl)-2-benzofuran-1-one
EINECS 204-729-7
5',5''-Diisopropyl-2',2''-dimethylphenolphthalein

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
571.6±50.0 °C at 760 mmHg

[ Melting Point ]:
251-253 °C(lit.)

[ Molecular Formula ]:
C28H30O4

[ Molecular Weight ]:
430.535

[ Flash Point ]:
187.5±23.6 °C

[ Exact Mass ]:
430.214417

[ PSA ]:
66.76000

[ LogP ]:
6.23

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.613

[ Storage condition ]:
Store at RT.

[ Water Solubility ]:
insoluble

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R40

[ Safety Phrases ]:
S7-S16-S36/37-S24/25-S22

[ RIDADR ]:
UN 1170 3/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
3

[ HS Code ]:
29322980

Synthetic Route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Thousands of chemical starting points for antimalarial lead identification.

Nature 465 , 305-10, (2010)

Malaria is a devastating infection caused by protozoa of the genus Plasmodium. Drug resistance is widespread, no new chemical class of antimalarials has been introduced into clinical practice since 19...

Experimental correlation between the pKa value of sulfonphthaleins with the nature of the substituents groups.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 69(4) , 1235-45, (2008)

This work presents the results obtained from a spectrophotometry study performed on some indicators of the sulfonphtaleins like phenol red (PR), thymol blue (TB), bromothymol blue (BTB), xylenol orang...

Analysis of nifedipine-acebutolol hydrochloride binary combination in tablets using UV-derivative spectroscopy, capillary gas chromatography and high performance liquid chromatography.

J. Pharm. Biomed. Anal. 16(1) , 21-30, (1997)

Three methods are described for the simultaneous determination of nifedipine and acebutolol hydrochloride in combined pharmaceutical tablets. The first method depends on first-derivative ultraviolet s...


More Articles


Related Compounds

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