EltroMbopag Methyl Ester

Names

[ Name ]:
EltroMbopag Methyl Ester

[Synonym ]:
Methyl 3'-{(2Z)-2-[1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene]hydrazino}-2'-hydroxy-3-biphenylcarboxylate
Eltrombopag Methyl Ester
[1,1'-Biphenyl]-3-carboxylic acid, 3'-[(2Z)-2-[1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-, methyl ester

Biological Activity

[Description]:

Eltrombopag methyl ester is a derivative of Eltrombopag, which is a thrombopoietin (Tpo) receptor agonist, which can promote platelet production and is used in research related to specific types of thrombocytopenia[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Immunology/Inflammation >> Thrombopoietin Receptor

[References]

[1]. Polymorphs of eltrombopag and eltrombopag salts and processes for preparation thereof. WO2010114943.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
626.5±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₆H₂₄N₄O₄

[ Molecular Weight ]:
456.49

[ Flash Point ]:
332.7±34.3 °C

[ Exact Mass ]:
456.179749

[ PSA ]:
103.59000

[ LogP ]:
3.82

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.641

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.