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Roy-Bz

Names

[ CAS No. ]:
1246304-91-5

[ Name ]:
Roy-Bz

Biological Activity

[Description]:

Roy-Bz is a selecive PKCδ activator. Roy-Bz potently inhibits the proliferation of colon cancer cells by inducing a PKCδ-dependent mitochondrial apoptotic pathway involving caspase-3 activation[1].

[Related Catalog]:

Signaling Pathways >> Epigenetics >> PKC
Signaling Pathways >> TGF-beta/Smad >> PKC

[Target]

PKCδ[1]


[References]

[1]. Bessa C, et al. Discovery of a small-molecule protein kinase Cδ-selective activator with promising application in colon cancer therapy. Cell Death Dis. 2018 Jan 18;9(2):23.

Chemical & Physical Properties

[ Molecular Formula ]:
C36H38O8

[ Molecular Weight ]:
598.68


Related Compounds

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