1-hexacosanoyl-d4-2-hydroxy-sn-glycero-3-phosphocholine

Names

[ Name ]:
1-hexacosanoyl-d4-2-hydroxy-sn-glycero-3-phosphocholine

[Synonym ]:
Ethanaminium, 2-[[hydroxy[(2R)-2-hydroxy-3-[(1-oxohexacosyl-12,12,13,13-d)oxy]propoxy]phosphinyl]oxy]-N,N,N-trimethyl-, inner salt
(2R)-3-[(12,12,13,13-H)Hexacosanoyloxy]-2-hydroxypropyl 2-(trimethylammonio)ethyl phosphate

Biological Activity

[Description]:

26:0 Lyso PC-d4 is deuterium labeled 26:0 Lyso PC.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₄H₆₆D₄NO₇P

[ Molecular Weight ]:
639.920

[ Exact Mass ]:
639.514099

[ LogP ]:
8.15