C3bot(154-182)

Names

[ Name ]:
C3bot(154-182)

[Synonym ]:
L-Threonine, L-valyl-L-alanyl-L-lysylglycyl-L-seryl-L-lysyl-L-alanylglycyl-L-tyrosyl-L-isoleucyl-L-α-aspartyl-L-prolyl-L-isoleucyl-L-seryl-L-alanyl-L-phenylalanyl-L-alanylglycyl-L-glutaminyl-L-leu cyl-L-α-glutamyl-L-methionyl-L-leucyl-L-leucyl-L-prolyl-L-arginyl-L-histidyl-L-seryl-
L-Valyl-L-alanyl-L-lysylglycyl-L-seryl-L-lysyl-L-alanylglycyl-L-tyrosyl-L-isoleucyl-L-α-aspartyl-L-prolyl-L-isoleucyl-L-seryl-L-alanyl-L-phenylalanyl-L-alanylglycyl-L-glutaminyl-L-leucyl-L-α-g lutamyl-L-methionyl-L-leucyl-L-leucyl-L-prolyl-L-arginyl-L-histidyl-L-seryl-L-threonine

Biological Activity

[Description]:

C3bot(154-182) is a C3 peptide enhances recovery from spinal cord injury by improving regenerative growth of descending fiber tracts. C3bot(154-182) represents a promising tool to foster axonal protection and/or repair, as well as functional recovery after traumatic CNS injury[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[In Vitro]

C3bot(154-182) stimulates regenerative growth of raphespinal fibers and improves serotonergic input to lumbar α-motoneurons[1].

[References]

[1]. Francesco Boato, et al. C3 peptide enhances recovery from spinal cord injury by improved regenerative growth of descending fiber tracts. J Cell Sci. 2010 May 15;123(Pt 10):1652-62.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C₁₃₇H₂₂₁N₃₇O₄₀S

[ Molecular Weight ]:
3058.510

[ Exact Mass ]:
3056.611816

[ LogP ]:
-0.74

[ Index of Refraction ]:
1.651

Related Compounds

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