PBFI-AM

Names

[ CAS No. ]:
124549-23-1

[ Name ]:
PBFI-AM

[Synonym ]:
Potassium indicator PBFI-AM,Potassium-binding benzofuran isophthalate-AM

Biological Activity

[Description]:

PBFI-AM is a useful tool to determine intracellular K+ content[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

[References]

[1]. B Andersson, et al. Induction of apoptosis by intracellular potassium ion depletion: using the fluorescent dye PBFI in a 96-well plate method in cultured lung cancer cells. Toxicol In Vitro. 2006 Sep;20(6):986-94.

Chemical & Physical Properties

[ Density]:
1.295g/cm3

[ Boiling Point ]:
1136.6ºC at 760 mmHg

[ Molecular Formula ]:
C₅₈H₆₂N₂O₂₄

[ Molecular Weight ]:
1171.11

[ Flash Point ]:
641.2ºC

[ Exact Mass ]:
1170.37000

[ PSA ]:
298.54000

[ LogP ]:
6.76280

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.559

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Granzyme B-induced neurotoxicity is mediated via activation of PAR-1 receptor and Kv1.3 channel.

PLoS ONE 7(8) , e43950, (2012)

Increasing evidence supports a critical role of T cells in neurodegeneration associated with acute and subacute brain inflammatory disorders. Granzyme B (GrB), released by activated T cells, is a cyto...

Fluorescent indicators for cytosolic sodium.

J. Biol. Chem. 264 , 19449, (1989)

Fluorescent indicators sensitive to cytosolic concentrations of free Na+ have been synthesized and characterized. They consist of a crown ether, 1,7-diaza-4,10,13-trioxacyclopentadecane, linked via it...

P. Jezek et al.

J. Biol. Chem. 264 , 10522, (1990)

Related Compounds

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