Ifidancitinib

Names

[ Name ]:
Ifidancitinib

[Synonym ]:
N-(4-{[(6S)-4-Hydroxy-2-(hydroxymethyl)-7,8-dihydro-6H-cyclopenta[g]quinazolin-6-yl](2-propyn-1-yl)amino}benzoyl)-γ-glutamylglutamic acid
Glutamic acid, N-[4-[[(6S)-7,8-dihydro-4-hydroxy-2-(hydroxymethyl)-6H-cyclopenta[g]quinazolin-6-yl]-2-propyn-1-ylamino]benzoyl]-γ-glutamyl-

Biological Activity

[Description]:

Ifidancitinib is a potent and selective inhibitor of JAK kinases 1/3. Ifidancitinib can be used in studies of allergies, asthma and autoimmune diseases[1].

[Related Catalog]:

Signaling Pathways >> JAK/STAT Signaling >> JAK

Signaling Pathways >> Epigenetics >> JAK

Signaling Pathways >> Stem Cell/Wnt >> JAK

Research Areas >> Others

[References]

[1]. Li, Hui; Heckrodt, Thilo J.; Chen, Yan; Mcmurtrie, Darren John; Taylor, Vanessa; Singh, Rajinder; Ding, Pingyu; Yen, Rose.Preparation of phenylaminopyrimidinylaminooxobenzooxazole derivatives for use as JAK kinase inhibitors. WO2012015972A1

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
1003.0±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₁₈FN₅O₃

[ Molecular Weight ]:
395.39

[ Flash Point ]:
560.4±34.3 °C

[ Exact Mass ]:
647.222717

[ LogP ]:
-1.15

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.693

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.