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ML132

Names

[ CAS No. ]:
1230628-71-3

[ Name ]:
ML132

Biological Activity

[Description]:

ML132 (NCGC 00185682) is a potent and selective caspase 1 inhibitor with an IC50 of 0.316 nM.

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Caspase
Research Areas >> Cancer

[Target]

IC50: 0.316 nM (Caspase 1)[1]


[References]

[1]. Boxer MB, et al. A highly potent and selective caspase 1 inhibitor that utilizes a key 3-cyanopropanoic acid moiety. ChemMedChem. 2010 May 3;5(5):730-8.


[Related Small Molecules]

Z-VAD(OMe)-FMK | VX-765 | QVD-OPh | Z-DEVD-FMK | Z-IETD-FMK | Sodium tauroursodeoxycholate | Ac-DEVD-CHO | Emricasan | PAC-1 | BOC-D-FMK | Taurochenodeoxycholic acid | 20(S)-Ginsenoside Rh2 | 2-HBA | Biotin-VAD-FMK | EP1013

Chemical & Physical Properties

No Any Chemical & Physical Properties