Compound 10

Names

[ Name ]:
Compound 10

[Synonym ]:
2-[4-[(2,4-Dioxo-5-thiazolidinylidene)methyl]phenoxy]-acetic acid
2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)acetic acid
GPR35 Agonist,Compound 10

Biological Activity

[Description]:

GPR35 agonist 3 is a synthetic GPR35 agonist with an EC50value of 1.4 μM. GPR35 agonist 3 can be used for the research of various diseases, such as gastric cancer, type 2 diabetes, cardiovascular diseases, immune system and peripheral nervous system[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Research Areas >> Inflammation/Immunology

Research Areas >> Metabolic Disease

Research Areas >> Neurological Disease

[Target]

EC50: 1.4 μM (GPR35)[1]. Ki: 0.0508 μM (GPR35)[1]. IC50: 0.349 μM (GPR35)[1].

[In Vitro]

GPR35 agonist 3 shows GPR35 agonist potency with an EC50 value of 1.4 μM[1]. GPR35 agonist 3 has affinity and potency for GPR35 with values of 0.0508μM (Ki) and 0.349 μM (IC50)[1].

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₉NO₅S

[ Molecular Weight ]:
279.26900

[ Exact Mass ]:
279.02000

[ PSA ]:
121.49000

[ LogP ]:
1.74980

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.