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CC214-2

Names

[ CAS No. ]:
1228012-18-7

[ Name ]:
CC214-2

Biological Activity

[Description]:

CC214-2 is a potent and dual inhibitor of mTORC1/mTORC2. Mycobacterium tuberculosis modulates mammalian target of rapamycin (mTOR) signaling to impede autophagy. CC214-2 has the potential to shorten the duration of TB[1].

[Related Catalog]:

Signaling Pathways >> PI3K/Akt/mTOR >> mTOR
Research Areas >> Cancer

[References]

[1]. Tasneen R, et al. Dual mTORC1/mTORC2 Inhibition as a Host-Directed Therapeutic Target in Pathologically Distinct Mouse Models of Tuberculosis. Antimicrob Agents Chemother. 2021;65(7):e0025321.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H25N5O3

[ Molecular Weight ]:
383.44


Related Compounds

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