Ovotransferrin (328-332) trifluoroacetate salt

Names

[ Name ]:
Ovotransferrin (328-332) trifluoroacetate salt

[Synonym ]:
L-Leucine, L-arginyl-L-valyl-L-prolyl-L-seryl-
L-Arginyl-L-valyl-L-prolyl-L-seryl-L-leucine

Biological Activity

[Description]:

Ovotransferrin (328-332) has a protective activity on the blood pressure by inhibiting the Angiotensin-Converting Enzyme (ACE), with the IC50 of 20 μM. Ovotransferrin (328-332) fragment has an activity against Cholinesterase (ChE), implicating in Alzheimer’s diseases[1][2].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)

Research Areas >> Neurological Disease

[Target]

ACE:20 μM (IC50)

[References]

[1]. Zhipeng Yu, et al. Primary and secondary structure of novel ACE-inhibitory peptides from egg white protein. Food Chem. 2012 Jul 15;133(2):315-22.

[2]. Zhipeng Yu, et al. Anti-Alzheimers activity and molecular mechanism of albumin-derived peptides against AChE and BChE. Food Funct. 2018 Feb 21;9(2):1173-1178.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₂₅H₄₆N₈O₇

[ Molecular Weight ]:
570.682

[ Exact Mass ]:
570.348938

[ LogP ]:
-0.57

[ Index of Refraction ]:
1.624

Related Compounds

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