MFZ 10-7

Names

[ Name ]:
MFZ 10-7

Biological Activity

[Description]:

MFZ 10-7 is a potent mGluR5 antagonist. Intraperitoneal administration of MFZ 10-7 inhibits intravenous cocaine self-administration, cocaine-induced reinstatement of drug-seeking behavior and cocaine-associated cue-induced cocaine-seeking behavior in rats[1]..

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> mGluR

Research Areas >> Neurological Disease

[Target]

mGluR5[1]

[References]

[1]. Keck TM, et al. A novel mGluR5 antagonist, MFZ 10-7, inhibits cocaine-taking and cocaine-seeking behavior in rats. Addict Biol.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₉FN₂

[ Molecular Weight ]:
236.24400

[ Exact Mass ]:
236.07500

[ PSA ]:
36.68000

[ LogP ]:
2.80058

Related Compounds

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