Eglin c (41-49)

Names

[ Name ]:
Eglin c (41-49)

[Synonym ]:
(3S)-4-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-1-[[(2S)-1,3-dihydroxy-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[(2S)-3-methyl-2-[[(2S)-pyrrolidine-2-carbonyl]amino]butanoyl]amino]butanoyl]amino]-4-methylpentanoyl]amino]-4-oxobutanoic acid
Eglin c (41-49)
H-Ser-Pro-Val-Thr-Leu-Asp-Leu-Arg-Tyr-OH
Ser-pro-val-thr-leu-asp-leu-arg-tyr-OH

Biological Activity

[Description]:

Eglin c (41-49) is a peptide fragment related to eglin c. Eglin c (41-49) shows inhibitory effects to cathepsin G and α-chymotrypsin with Ki values of 42 and 20 μM, respectively[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Okada Y, et al. Synthesis of peptide fragments related to eglin c and examination of their inhibitory effect on human leukocyte elastase, cathepsin G and alpha-chymotrypsin. Biochem Biophys Res Commun. 1989 May 30;161(1):272-5.

Chemical & Physical Properties

[ Density]:
1.44 g/cm3

[ Molecular Formula ]:
C₄₈H₇₈N₁₂O₁₅

[ Molecular Weight ]:
1063.20000

[ Exact Mass ]:
1062.57000

[ PSA ]:
469.94000

[ LogP ]:
4.75110

[ Index of Refraction ]:
1.635

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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