NSC 190686-d3

Names

[ CAS No. ]:
1219798-70-5

[ Name ]:
NSC 190686-d3

[Synonym ]:
Benzoic acid, 3,4-difluoro-
3,4-Difluorobenzoic acid
QVR CF DF
2085848

Biological Activity

[Description]:

NSC 190686-d3 is the deuterium labeled NSC 190686[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
257.0±20.0 °C at 760 mmHg

[ Molecular Formula ]:
C7H4F2O2

[ Molecular Weight ]:
158.102

[ Flash Point ]:
109.2±21.8 °C

[ Exact Mass ]:
158.017929

[ LogP ]:
2.25

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.513

Related Compounds