AC-SER-GLN-ASN-TYR-PRO-VAL-VAL-NH2

Names

[ Name ]:
AC-SER-GLN-ASN-TYR-PRO-VAL-VAL-NH2

[Synonym ]:
Acetyl-Ser-Gln-Asn-Tyr-Pro-Val-Val amide

Biological Activity

[Description]:

Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2 is a substrato peptídico of HIV-1 protease.Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2 acts as the variable substrate in a peptidolytic assay to quantify the inhibition of the protease[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Metabolic Enzyme/Protease >> HIV Protease

[References]

[1]. Ana C. R. Sodero, et al. Mecanismo Catalítico e Estado de Protonação do Sítio Ativo de Aspartil Proteases Pepsina-Símiles.Revista Virtual de Química, v. 1 n. 2 (2009).

[2]. G B Dreyer, et al. Inhibition of human immunodeficiency virus 1 protease in vitro: rational design of substrate analogue inhibitors. Proc Natl Acad Sci U S A. 1989 Dec;86(24):9752-6.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₈H₅₈N₁₀O₁₂

[ Molecular Weight ]:
846.92700

[ Exact Mass ]:
846.42400

[ PSA ]:
364.64000

[ LogP ]:
0.16910

MSDS

Click to get detail MSDS

Related Compounds

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