Garenoxacin-d4

Names

[ CAS No. ]:
1217818-32-0

[ Name ]:
Garenoxacin-d4

Biological Activity

[Description]:

Garenoxacin-d4 (BMS284756-d4) is the deuterium labeled Garenoxacin. Garenoxacin (BMS284756) is a quinolone antibiotic for the treatment of Gram-positive and Gram-negative bacterial infections[1][2].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Takagi H, et al. Clinical studies of garenoxacin. Int J Antimicrob Agents. 2008;32(6):468-474.

Chemical & Physical Properties

[ Molecular Formula ]:
C23H16D4F2N2O4

[ Molecular Weight ]:
430.44

Related Compounds