Furazolidone-D4

Names

[ Name ]:
Furazolidone-D4

[Synonym ]:
Furaxon-d4
Furazolidon-d4
Tikofuran-d4
Diafuron-d4
Giardil-d4
Furazolidone-d4
Trifurox-d4
Topazone-d4
Roptazol-d4
Furazol-d4

Biological Activity

[Description]:

Furazolidone-d4 is deuterium labeled Furazolidone.

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Jiang X, et al. A novel application of furazolidone: anti-leukemic activity in acute myeloid leukemia. PLoS One. 2013 Aug 9;8(8):e72335.

Chemical & Physical Properties

[ Molecular Formula ]:
C₈H₃D₄N₃O₅

[ Molecular Weight ]:
229.18

[ Exact Mass ]:
229.06400

[ PSA ]:
100.86000

[ LogP ]:
1.43500

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H361

[ Precautionary Statements ]:
P281

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
62

[ Safety Phrases ]:
36/37

[ RIDADR ]:
NONH for all modes of transport