A 350619 hydrochloride

Names

[ Name ]:
A 350619 hydrochloride

[Synonym ]:
2-Propenamide, 3-[2-[(4-chlorophenyl)thio]phenyl]-N-[4-(dimethylamino)butyl]-, (2E)-, hydrochloride (1:1)
(2E)-3-{2-[(4-Chlorophenyl)sulfanyl]phenyl}-N-[4-(dimethylamino)butyl]acrylamide hydrochloride (1:1)

Biological Activity

[Description]:

A-350619 hydrochloride is a soluble guanylate cyclase (sGC) activator. A-350619 hydrochloride can be used in the study of erectile dysfunction[1][2].

[Related Catalog]:

Research Areas >> Others

[Target]

sGC[1][2].

[References]

[1]. Kotzki S, et al. Anodal iontophoresis of a soluble guanylate cyclase stimulator induces a sustained increase in skin blood flow in rats. J Pharmacol Exp Ther. 2013 Sep;346(3):424-31.

[2]. Miller LN, et al. A-350619: a novel activator of soluble guanylyl cyclase. Life Sci. 2003 Jan 17;72(9):1015-25.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₆Cl₂N₂OS

[ Molecular Weight ]:
425.41

[ Exact Mass ]:
424.114288

Related Compounds

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