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Fluo-3AM

Names

[ CAS No. ]:
121714-22-5

[ Name ]:
Fluo-3AM

[Synonym ]:
Acetoxymethyl {[2-(acetoxymethoxy)-2-oxoethyl](2-{2-[2-{bis[2-(acetoxymethoxy)-2-oxoethyl]amino}-5-(2,7-dichloro-6-hydroxy-3-oxo-3H-xanthen-9-yl)phenoxy]ethoxy}-4-methylphenyl)amino}acetate
4-(6-Acetoxymethoxy-2,7-dichloro-3-oxo-9-xanthenyl)-4'-methyl-2,2'(ethylenedioxy)dianiline-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl) ester
MFCD00083336
Fluo 3-AM
Fluo-3AM

Biological Activity

[Description]:

Fluo-3AM(Fluo-3-pentaacetoxymethyl ester) is a calcium indicator that exhibit an increase in fluorescence upon binding Ca2+; used to image the spatial dynamics of Ca2+ signaling, in flow cytometry experiments involving photoactivation of caged chelators, second messengers, and neurotransmitters, and for cell-based pharmacological screening.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Dye Reagents
Research Areas >> Others

[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
1075.8±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C51H50Cl2N2O23

[ Molecular Weight ]:
1129.85

[ Flash Point ]:
604.4±34.3 °C

[ PSA ]:
285.78000

[ LogP ]:
5.40

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.631

[ Storage condition ]:
−20°C

[ Water Solubility ]:
DMSO: soluble

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Role of dopamine D2 receptors in ischemia/reperfusion induced apoptosis of cultured neonatal rat cardiomyocytes.

J. Biomed. Sci. 18 , 18, (2011)

Myocardial ischemia/reperfusion injury is the major cause of morbidity and mortality for cardiovascular diseases. Dopamine D2 receptors are expressed in cardiac tissues. However, the roles of dopamine...


More Articles

Related Compounds

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