CGP 20712 dihydrochloride

Names

[ Name ]:
CGP 20712 dihydrochloride

[Synonym ]:
Benzamide, 2-hydroxy-5-[2-[[2-hydroxy-3-[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenoxy]propyl]amino]ethoxy]-, hydrochloride (1:2)
2-Hydroxy-5-{2-[(2-hydroxy-3-{4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenoxy}propyl)amino]ethoxy}benzamide dihydrochloride

Biological Activity

[Description]:

CGP 20712 dihydrochloride is an antagonist of β 3-adrenoceptor. CGP 20712 dihydrochloride inhibits isoproterenol with the IC50 of 79 μM[1].

[Related Catalog]:

Research Areas >> Endocrinology

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

Research Areas >> Neurological Disease

[References]

[1]. Van Liefde I, et al. Isoproterenol and selective agonists stimulate similar atypical beta-adrenoceptors in rat adipocytes. Biochem Pharmacol. 1993 Feb 24;45(4):974-7.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₇Cl₂F₃N₄O₅

[ Molecular Weight ]:
567.39

[ Exact Mass ]:
566.131042

Related Compounds

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