(Rac)-LM11A-31 dihydrochloride

Names

[ Name ]:
(Rac)-LM11A-31 dihydrochloride

[Synonym ]:
MFCD11505486

Biological Activity

[Description]:

(Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a p75NTR (neurotrophin receptor p75) Ligand, is a potent proNGF (nerve growth factor) antagonist[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Elshaer SL, et al. Modulation of the p75 neurotrophin receptor using LM11A-31 prevents diabetes-induced retinalvascular permeability in mice via inhibition of inflammation and the RhoA kinase pathway. Diabetologia. 2019 Aug;62(8):1488-1500.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₂H₂₇Cl₂N₃O₂

[ Molecular Weight ]:
316.27

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335-H410

[ Precautionary Statements ]:
P261-P273-P305 + P351 + P338-P501

[ Hazard Codes ]:
N

[ RIDADR ]:
UN 3077 9 / PGIII

Related Compounds

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