GSK2556286

Names

[ Name ]:
GSK2556286

Biological Activity

[Description]:

GSK2556286 (GSK286) is an orally active inhibitor of M. tuberculosis. GSK2556286 inhibits growth within human macrophages (IC50 = 0.07 μM). GSK2556286 is effective against both multidrug-resistant (MDR) or extensively drug-resistant (XDR) and drug-sensitive (DS) M. tuberculosis[1].

[Related Catalog]:

Research Areas >> Infection

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Anti-infection >> Bacterial

[Target]

IC50: 0.07 μM (human macrophage)[1]

[References]

[1]. Nuermberger EL, et al. GSK2556286 Is a Novel Antitubercular Drug Candidate Effective In Vivo with the Potential To Shorten Tuberculosis Treatment. Antimicrob Agents Chemother. 2022 May 24:e0013222.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₂₃N₃O₃

[ Molecular Weight ]:
329.39

Related Compounds

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