Ethyl vanillin
Names
[ CAS No. ]:
121-32-4
[ Name ]:
Ethyl vanillin
[Synonym ]:
burbonal
FEMA 2464
vanirome
EINECS 204-464-7
Bourbonal
3-Ethoxy-4-hydroxybenzaldehyde,Ethylvanillin
Vanilal
VANILLAL
ETHOVAN
3-ethoxy
VHR DQ CO2
ethylvanillin
4-hydroxy-3-ethoxybenzaldehyde
4-OH-3-OEtC6H3CHO
Vanirom
3-Ethoxy-4-hydroxybenzaldehyde
Vanbeenol
MFCD00006944
Ethyl Vanillin
Benzaldehyde, 3-ethoxy-4-hydroxy-
Ethavan
Biological Activity
[Description]:
[Related Catalog]:
[Related Small Molecules]
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
295.1±20.0 °C at 760 mmHg
[ Melting Point ]:
76 °C
[ Molecular Formula ]:
C9H10O3
[ Molecular Weight ]:
166.174
[ Flash Point ]:
119.0±15.3 °C
[ Exact Mass ]:
166.062988
[ PSA ]:
46.53000
[ LogP ]:
1.72
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.574
[ Water Solubility ]:
slightly soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CU6125000
- CHEMICAL NAME :
- Benzaldehyde, 3-ethoxy-4-hydroxy-
- CAS REGISTRY NUMBER :
- 121-32-4
- BEILSTEIN REFERENCE NO. :
- 1073761
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 16
- MOLECULAR FORMULA :
- C9-H10-O3
- MOLECULAR WEIGHT :
- 166.19
- WISWESSER LINE NOTATION :
- VHR DQ CO2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Human
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1590 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 750 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 760 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >7940 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 1140 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4480 mg/kg/70D-I
- TOXIC EFFECTS :
- Cardiac - other changes Blood - changes in spleen Nutritional and Gross Metabolic - weight loss or decreased weight gain
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Rodent - hamster Fibroblast
- DOSE/DURATION :
- 250 mg/L
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 22,623,1984 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4743 No. of Facilities: 26 (estimated) No. of Industries: 2 No. of Occupations: 17 No. of Employees: 2343 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4743 No. of Facilities: 2917 (estimated) No. of Industries: 20 No. of Occupations: 42 No. of Employees: 53949 (estimated) No. of Female Employees: 31080 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
1
[ RTECS ]:
CU6125000
[ Packaging Group ]:
I; II; III
[ HS Code ]:
2912420000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2912420000
[ Summary ]:
2912420000 3-ethoxy-4-hydroxybenzaldehyde。Supervision conditions:None。VAT:17.0%。Tax rebate rate:13.0%。Lowest tariff:5.5%。General tariff:30.0%
Articles
Zhong Yao Cai 33(4) , 545-6, (2010)
To study the chemical constituents from the marine sponge Iotrochota sp.The compounds were isolated and purified by various column chromatography methods, and their structure wer identified cholestero...
Thermal tolerance and survival of Cronobacter sakazakii in powdered infant formula supplemented with vanillin, ethyl vanillin, and vanillic acid.J. Food Sci. 77(9) , M523-7, (2012)
The thermal tolerance Cronobacter sakazakii was examined in sterile powdered infant formula (PIF) rehydrated at 58 °C in water or apple juice supplemented with vanillin, ethyl vanillin, or vanillic ac...
Dihydroagarofuranoid sesquiterpenes, a lignan derivative, a benzenoid, and antitubercular constituents from the stem of Microtropis japonica.J. Nat. Prod. 71 , 1016-21, (2008)
Four new compounds, including two new dihydroagarofuranoid sesquiterpenes, 8-benzoyloxymutangin (1) and 15-acetoxyorbiculin G (2), a new lignan derivative, 9,9'- O-di-(Z)-feruloyl-(-)-secoisolaricires...