glycine beta-naphthylamide hydrochloride

Names

[ CAS No. ]:
1208-12-4

[ Name ]:
glycine beta-naphthylamide hydrochloride

[Synonym ]:
Glycine |A-naphthylamide hydrochloride
EINECS 214-899-4
2-Amino-N-2-naphthylacetamide HCl

Biological Activity

[Description]:

Glycine β-naphthylamide hydrochloride is a Glycine (HY-Y0966) derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Boiling Point ]:
453.8ºC at 760 mmHg

[ Molecular Formula ]:
C₁₂H₁₃ClN₂O

[ Molecular Weight ]:
236.69700

[ Flash Point ]:
228.2ºC

[ Exact Mass ]:
236.07200

[ PSA ]:
55.12000

[ LogP ]:
3.31230

[ Vapour Pressure ]:
2.01E-08mmHg at 25°C

[ Storage condition ]:
−20°C

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H351

[ Precautionary Statements ]:
P281

[ Personal Protective Equipment ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R40

[ Safety Phrases ]:
22-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Purification and characterization of proline-beta-naphthylamidase, a novel enzyme from pig intestinal mucosa.

J. Biol. Chem. 264 , 11565, (1989)

An enzyme hydrolyzing proline-beta-naphthylamide was purified to apparent homogeneity from porcine intestinal mucosa. The purified enzyme appears to consist of three identical subunit polypeptides wit...

Recombinant porcine intestinal carboxylesterase: cloning from the pig liver esterase gene by site-directed mutagenesis, functional expression and characterization.

Protein Eng. 16 , 1139-1145, (2003)

It was shown recently that proline-beta-naphthylamidase from pig liver resembles the gamma-subunit of pig liver esterase (PLE), which could be functionally expressed in the yeast Pichia pastoris in re...

Interactions among challenges of hydromineral balance, angiotensin-converting enzyme, and cystine aminopeptidase.

Peptides 22 , 2137-2144, (2001)

Enzymatic cleavage of some peptides could be included among the mechanisms of water-electrolyte homeostasis. To test this hypothesis, the angiotensin-converting activity (ACE) of plasma and the L-cyst...