Scutebata E

Names

[ CAS No. ]:
1207181-61-0

[ Name ]:
Scutebata E

[Synonym ]:
(3S,4aR,5S,6R,6aR,10R,10aS,10bR)-5,6-Diacetoxy-4a,6a,7,10b-tetramethyl-5'-oxo-1,2,4',4a,5,5',6,6a,9,10,10a,10b-dodecahydrospiro[benzo[f]chromene-3,3'-furan]-10-yl 2-methylpropanoate
Propanoic acid, 2-methyl-, (3S,4a'R,5'S,6'R,6a'R,10'R,10a'S,10b'R)-5',6'-bis(acetyloxy)-1',2',4,4'a,5,5',6',6'a,9',10',10'a,10'b-dodecahydro-4'a,6'a,7',10'b-tetramethyl-5-oxospiro[furan-3(2H),3'-[3H]naphtho[2,1-b]pyran]-10'-yl ester

Biological Activity

[Description]:

Scutebata E is a new neoclerodane diterpenoid isolated from Scutellaria barbata with weak cytotoxic activity[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Scutebata E 具有弱细胞毒性，对 LoVo 细胞的 IC50 值为61.23 μM，对 MCF-7、SMMC-7721 和 HCT-116 细胞的 IC50 值均大于100 μM[1]。

[References]

[1]. Wang M, et al. Cytotoxic Neo-Clerodane Diterpenoids from Scutellaria barbata D.Don. Chem Biodivers. 2019 Feb;16(2):e1800499.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
592.2±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₈H₄₀O₉

[ Molecular Weight ]:
520.61

[ Flash Point ]:
248.7±30.2 °C

[ Exact Mass ]:
520.267212

[ PSA ]:
114.43000

[ LogP ]:
3.58

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.532

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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