Scutebata B

Names

[ CAS No. ]:
1207181-58-5

[ Name ]:
Scutebata B

[Synonym ]:
(1R,2S,3R,4S,4aS,8aR)-4-[(1S)-1-Acetoxy-2-(4-hydroxy-5-oxo-2,5-dihydro-3-furanyl)ethyl]-2-(benzoyloxy)-3-hydroxy-3,4,8,8a-tetramethyl-1,2,3,4,4a,5,6,8a-octahydro-1-naphthalenyl nicotinate
3-Pyridinecarboxylic acid, (1R,2S,3R,4S,4aS,8aR)-4-[(1S)-1-(acetyloxy)-2-(2,5-dihydro-4-hydroxy-5-oxo-3-furanyl)ethyl]-2-(benzoyloxy)-1,2,3,4,4a,5,6,8a-octahydro-3-hydroxy-3,4,8,8a-tetramethyl-1-naphthalenyl ester

Biological Activity

[Description]:

Scutebata B (compound 4) is a neoclerodane diterpenoid iaolated from the whole plant of Scutellaria barbata. Scutebata B has cytotoxic activities with IC50 values of 10.27～28.48 μM[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[Target]

IC50 10.73 μM (LoVo cell), 18.96 μM (SMMC-7721 cell), 10.27 μM (MCF-7 cell), 28.48 μM (HCT-116 cell)[1]

[References]

[1]. Maolin Wang, et al. Neoclerodane diterpenoids from Scutellaria barbata with cytotoxic activities. Nat Prod Res. 2020, 34, 10.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
797.3±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₅H₃₉NO₁₀

[ Molecular Weight ]:
633.68

[ Flash Point ]:
436.0±32.9 °C

[ Exact Mass ]:
633.257385

[ PSA ]:
158.55000

[ LogP ]:
5.04

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.612

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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