N-Carbethoxy Piperazine

Names

[ CAS No. ]:
120-43-4

[ Name ]:
N-Carbethoxy Piperazine

[Synonym ]:
N-Carbethoxy Piperazine
Ethyl N-Piperazinecarboxylate
1-Piperazinecarboxylic acid, ethyl ester
1-Ethoxycarbonylpiperazine
Ethyl Piperazine-1-Carboxylate
MFCD00005964
1-Piperazinecarboxylic Acid Ethyl Ester
EINECS 204-395-2
Ethyl 1-piperazinecarboxylate

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
237.0±15.0 °C at 760 mmHg

[ Melting Point ]:
120 °C

[ Molecular Formula ]:
C₇H₁₄N₂O₂

[ Molecular Weight ]:
158.198

[ Flash Point ]:
97.1±20.4 °C

[ Exact Mass ]:
158.105530

[ PSA ]:
41.57000

[ LogP ]:
-0.14

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.467

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TL1378000

CHEMICAL NAME :: 1-Piperazinecarboxylic acid, ethyl ester

CAS REGISTRY NUMBER :: 120-43-4

BEILSTEIN REFERENCE NO. :: 0125780

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C7-H14-N2-O2

MOLECULAR WEIGHT :: 158.23

WISWESSER LINE NOTATION :: T6M DNTJ AVO2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 138 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - muscle contraction or spasticity

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 33,825,1987

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S23-S24/25-S37/39-S26

[ RIDADR ]:
UN 2810 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
TL1378000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
29335995

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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