RBP4 inhibitor 1

Names

[ CAS No. ]:
1198180-03-8

[ Name ]:
RBP4 inhibitor 1

Biological Activity

[Description]:

RBP4 inhibitor 1 (compound 43b) is a potent and orally active retinol-binding protein 4 (RBP4) inhibitor with IC50s of 28 nM and 110 nM for human and mouse RBP4. RBP4 inhibitor 1 has a potent and long-lasting blood RBP4-level-reducing effect in mice[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[Target]

IC50: 28 nM (human RBP4) and 110 nM (mouse RBP4)[1]

[References]

[1]. Shinji Nakamura, et al. Discovery of phenylpyrrolidine derivatives as a novel class of retinol binding protein 4 (RBP4) reducers. Bioorg Med Chem. 2022 Jan 15;54:116553.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₁₃F₆NO₃

[ Molecular Weight ]:
357.25

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.