1198180-03-8

1198180-03-8 structure

Name: RBP4 inhibitor 1
Chemical Name: RBP4 inhibitor 1
CAS Number: 1198180-03-8
Molecular Formula: C₁₄H₁₃F₆NO₃
Molecular Weight: 357.25
Catalog: Research Areas Metabolic Disease
Create Date: 2022-05-27 14:51:14
Modify Date: 2025-08-26 10:45:58
RBP4 inhibitor 1 (compound 43b) is a potent and orally active retinol-binding protein 4 (RBP4) inhibitor with IC50s of 28 nM and 110 nM for human and mouse RBP4. RBP4 inhibitor 1 has a potent and long-lasting blood RBP4-level-reducing effect in mice[1].

Name	RBP4 inhibitor 1

Description	RBP4 inhibitor 1 (compound 43b) is a potent and orally active retinol-binding protein 4 (RBP4) inhibitor with IC50s of 28 nM and 110 nM for human and mouse RBP4. RBP4 inhibitor 1 has a potent and long-lasting blood RBP4-level-reducing effect in mice[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
Target	IC50: 28 nM (human RBP4) and 110 nM (mouse RBP4)[1]
References	[1]. Shinji Nakamura, et al. Discovery of phenylpyrrolidine derivatives as a novel class of retinol binding protein 4 (RBP4) reducers. Bioorg Med Chem. 2022 Jan 15;54:116553.

Molecular Formula	C₁₄H₁₃F₆NO₃
Molecular Weight	357.25