clerodendrin

Names

[ CAS No. ]:
119738-57-7

[ Name ]:
clerodendrin

[Synonym ]:
Clerodendrin

Biological Activity

[Description]:

Clerodendrin is a nature product could be isolated from Lobelia chinensis. Clerodendrin is a potent dual Interleukin-4 (IL-4) inhibitor and β-hexosaminidase (Hex) inhibitor[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Interleukin Related

Research Areas >> Inflammation/Immunology

[In Vitro]

Clerodendrin (10 μM; 1 and 3 h) inhibits IL-4 mRNA expression and the release of β-hexosaminidase in Propidium Iodide (HY-D0815)-induced RBL-2H3 cells[1].

[References]

[1]. Young KT, et, al. Inhibition of Interleukin-4 and β-Hexosaminidase Release in RBL-2H3 Cells by Compounds Isolated from Lobelia chinensis. 2021,27(4):251-6.

Chemical & Physical Properties

[ Density]:
1.88g/cm3

[ Boiling Point ]:
1057.6ºC at 760mmHg

[ Molecular Formula ]:
C₂₇H₂₆O₁₇

[ Molecular Weight ]:
622.48500

[ Flash Point ]:
349.9ºC

[ Exact Mass ]:
622.11700

[ PSA ]:
283.34000

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.766

[ Storage condition ]:
2-8°C

Related Compounds

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