Edivoxetine hydrochloride

Names

[ CAS No. ]:
1194374-05-4

[ Name ]:
Edivoxetine hydrochloride

[Synonym ]:
EDIVOXETINE HYDROCHLORIDE
Edivoxetine hydrochoride
Edivoxetine HCl

Biological Activity

[Description]:

Edivoxetine (hydrochloride) is a selective and potent norepinephrine reuptake inhibitor (NERI) being used in depressive disorder or attention-deficit/hyperactivity disorder.

[Related Catalog]:

Research Areas >> Neurological Disease

[References]

[1]. Jin L, Xu W, Krefetz D, et al. Clinical outcomes from an open-label study of edivoxetine use in pediatric patients with attention-deficit/hyperactivity disorder. J Child Adolesc Psychopharmacol. 2013;23(3):200-207.

[2]. Kielbasa W, Tesfaye E, Luffer-Atlas D, Mitchell MI, Turik MA. The effect of hepatic or renal impairment on the pharmacokinetics of edivoxetine, a selective norepinephrine transporter reuptake inhibitor. Eur J Clin Pharmacol. 2013;69(12):2011-2019.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₂₇ClFNO₄

[ Molecular Weight ]:
375.86300

[ Exact Mass ]:
375.16100

[ PSA ]:
59.95000

[ LogP ]:
2.65370

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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