Loratadine Impurity 16

Names

[ CAS No. ]:
119410-08-1

[ Name ]:
Loratadine Impurity 16

[Synonym ]:
8-Chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-3-ol
8-chloro-11-piperidin-4-ylidene-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-3-ol
Loratadine Impurity 16

Biological Activity

[Description]:

3-Hydroxy desloratidine is a metabolite of desloratidine[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Melton Affrime, et al. A pharmacokinetic profile of desloratadine in healthy adults, including elderly. Clin Pharmacokinet. 2002;41 Suppl 1:13-9.

Chemical & Physical Properties

[ Density]:
1.293g/cm3

[ Boiling Point ]:
575.2ºC at 760 mmHg

[ Melting Point ]:
169-171ºC

[ Molecular Formula ]:
C₁₉H₁₉ClN₂O

[ Molecular Weight ]:
326.82

[ Flash Point ]:
301.67ºC

[ Exact Mass ]:
326.11900

[ PSA ]:
45.15000

[ LogP ]:
4.05330

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.647

Safety Information

[ HS Code ]:
2933990090

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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