2-Iodo-2'-deoxyadenosine

Names

[ Name ]:
2-Iodo-2'-deoxyadenosine

[Synonym ]:
2'-Deoxy-2-iodoadenosine
Adenosine, 2'-deoxy-2-iodo-

Biological Activity

[Description]:

2′-Deoxy-2-iodoadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
2.5±0.1 g/cm3

[ Boiling Point ]:
729.7±70.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₀H₁₂IN₅O₃

[ Molecular Weight ]:
377.14

[ Flash Point ]:
395.1±35.7 °C

[ Exact Mass ]:
376.998474

[ LogP ]:
-0.56

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.951

2-Iodo-2'-deoxyadenosine

Names

Biological Activity

Chemical & Physical Properties

Related Compounds