2,2-dimethylvaleric acid
Names
[ CAS No. ]:
1185-39-3
[ Name ]:
2,2-dimethylvaleric acid
[Synonym ]:
2,2-Dimethylpentanoic Acid
2,2-Dimethylvaleric Acid
EINECS 214-682-4
MFCD00021686
Chemical & Physical Properties
[ Density]:
0.918 g/mL at 20 °C(lit.)
[ Boiling Point ]:
200-205°C
[ Molecular Formula ]:
C7H14O2
[ Molecular Weight ]:
130.18500
[ Flash Point ]:
200-205°C
[ Exact Mass ]:
130.09900
[ PSA ]:
37.30000
[ LogP ]:
1.89730
[ Vapour Pressure ]:
0.0889mmHg at 25°C
[ Index of Refraction ]:
n20/D 1.422
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YV6487500
- CHEMICAL NAME :
- Valeric acid, 2,2-dimethyl-
- CAS REGISTRY NUMBER :
- 1185-39-3
- BEILSTEIN REFERENCE NO. :
- 1747703
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C7-H14-O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- REFERENCE :
- NEPHBW Neuropharmacology. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.9- 1970- Volume(issue)/page/year: 24,427,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 740 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- REFERENCE :
- NEPHBW Neuropharmacology. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.9- 1970- Volume(issue)/page/year: 24,427,1985
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
C: Corrosive;
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 3265 8/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
YV6487500
[ Packaging Group ]:
II
[ Hazard Class ]:
8
[ HS Code ]:
2915900090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2915900090
[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%
Articles
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 862(1-2) , 168-74, (2008)
2,2-Dimethylbutyrate (DMB) is a potential treatment for thalassemia and hemoglobinopathies. To facilitate pharmacokinetic evaluation of DMB, we developed an LC-MS assay and quantitated DMB in plasma o...
Effects of branched-chain fatty acids on GABA-degradation and behavior: further evidence for a role of GABA in quasi-morphine abstinence behavior.Pharmacol. Biochem. Behav. 13(6) , 843-9, (1980)
An increase in GABA-ergic activity has been implicated in the initiation of quasi-morphine abstinence behavior by di-n-propylacetate (DPA). Two structural analogues of DPA, namely, the branched-chain-...
Effects of the lipid regulator drug gemfibrozil: A toxicological and behavioral perspective.Aquat. Toxicol. 170 , 355-64, (2016)
Pharmaceuticals are emerging contaminants as their worldwide consumption increases. Fibrates such as gemfibrozil (GEM) are used in human medicine to reduce blood concentrations of cholesterol and tria...