1,3,3 TRIMETHYL-2-METHYLENE INDOLINE
Names
[ CAS No. ]:
118-12-7
[ Name ]:
1,3,3 TRIMETHYL-2-METHYLENE INDOLINE
[Synonym ]:
1,3,3-trimethyl-2-methylideneindole
1,3,3-TriMethyl-2-Methyleneindoline
MFCD00005813
EINECS 204-235-1
Fischer's Base
2-Methylene-1,3,3-trimethylindoline,Fischer base
1,3,3 TRIMETHYL-2-METHYLENE INDOLINE
Chemical & Physical Properties
[ Density]:
0.979 g/mL at 25 °C(lit.)
[ Boiling Point ]:
248 °C(lit.)
[ Melting Point ]:
-8 °C
[ Molecular Formula ]:
C12H15N
[ Molecular Weight ]:
173.25400
[ Flash Point ]:
215 °F
[ Exact Mass ]:
173.12000
[ PSA ]:
3.24000
[ LogP ]:
2.99270
[ Vapour Pressure ]:
0.0249mmHg at 25°C
[ Index of Refraction ]:
n20/D 1.577(lit.)
[ Water Solubility ]:
negligible
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NM1926500
- CHEMICAL NAME :
- Indoline, 2-methylene-1,3,3-trimethyl-
- CAS REGISTRY NUMBER :
- 118-12-7
- BEILSTEIN REFERENCE NO. :
- 0131162
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C12-H15-N
- MOLECULAR WEIGHT :
- 173.28
- WISWESSER LINE NOTATION :
- T56 BNY DHJ B1 CU1 D1 D1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#07782 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6185 No. of Facilities: 45 (estimated) No. of Industries: 3 No. of Occupations: 4 No. of Employees: 775 (estimated) No. of Female Employees: 20 (estimated)
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H400
[ Precautionary Statements ]:
P273
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R22;R38;R50/53
[ Safety Phrases ]:
S28-S60-S61-S57-S37
[ RIDADR ]:
UN 3082 9/PG 3
[ WGK Germany ]:
2
[ RTECS ]:
NM1926500
[ Hazard Class ]:
9.0
[ HS Code ]:
29339990
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Angew. Chem. Int. Ed. Engl. 66 , 555, (1954)
Ishmetova, R., I.; et al.
Heterocycles 83 , 1363, (2011)
York, M.; Evans, R., A.
Tetrahedron Lett. 51 , 2195, (2010)