TNPAL-Sphingomyelin

Names

[ Name ]:
TNPAL-Sphingomyelin

[Synonym ]:
[(E)-3-hydroxy-2-[12-(2,4,6-trinitroanilino)dodecanoylamino]octadec-4-enyl] 2-(trimethylazaniumyl)ethyl phosphate
MFCD00133879
Trinitrophenylaminolauroylsphingomyelin

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₁H₇₃N₆O₁₂P

[ Molecular Weight ]:
873.02500

[ Flash Point ]:
11ºC

[ Exact Mass ]:
872.50200

[ PSA ]:
270.71000

[ LogP ]:
12.58800

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H302 + H312-H315-H319-H331-H336-H351-H361d-H370-H372

[ Precautionary Statements ]:
P201-P210-P260-P280-P304 + P340 + P312-P370 + P378

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F: Flammable;T: Toxic;

[ Risk Phrases ]:
45-46-11-23/24/25-36/37/38-48/20/22-40-39/23/24/25-38

[ Safety Phrases ]:
53-16-23-45-36/37

[ RIDADR ]:
UN 1230 3/PG 2

Articles

Rapid phase change of lipid microdomains in giant vesicles induced by conversion of sphingomyelin to ceramide.

Biochim. Biophys. Acta 1758(2) , 145-53, (2006)

To understand the role of sphingomyelinase (SMase) in the function of biological membranes, we have investigated the effect of conversion of sphingomyelin (SM) to ceramide (Cer) on the assembly of dom...

Interaction between sphingomyelin and oxysterols contributes to atherosclerosis and sudden death.

Am. J. Cardiovasc. Dis. 3(1) , 17-26, (2013)

Despite major public health efforts, coronary heart disease continues to be the leading cause of death in the United States. Oxidized lipids contribute to heart disease both by increasing deposition o...

Sphingomyelin metabolism at the plasma membrane: Implications for bioactive sphingolipids

FEBS Lett. 584(9) , 1887-94, (2010)

The plasma membrane (PM) is a major resource for production of bioactive lipids and contains a large proportion of the cellular sphingomyelin (SM) content. Consequently, the regulation of SM levels at...