ZINC13466751

Names

[ CAS No. ]:
117953-17-0

[ Name ]:
ZINC13466751

Biological Activity

[Description]:

ZINC13466751 is a potent inhibitor of HIF-1α/von Hippel-Lindau interaction with an IC50 of 2.0 µM[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase

[Target]

IC50: 2.0 µM (HIF-1α/von Hippel-Lindau)[1]

[References]

[1]. Xue X, et al. Discovery of novel inhibitors disrupting HIF-1α/von Hippel-Lindau interaction through shape-based screening and cascade docking. PeerJ. 2016 Dec 15;4:e2757.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₁N₅O₂

[ Molecular Weight ]:
363.41

Related Compounds

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