Lanopepden

Names

[ Name ]:
Lanopepden

[Synonym ]:
gsk-322
unii-12m6kfd07e

Biological Activity

[Description]:

Lanopepden (GSK 1322322) is a peptide deformylase inhibitor active against Staphylococcus aureus strains with MICs of 1 and 1 mg/L for ATCC 29213 and ATCC 25923 strain, respectively[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Peyrusson F, et al. Cellular pharmacokinetics and intracellular activity of the novel peptide deformylase inhibitor GSK1322322 against Staphylococcus aureus laboratory and clinical strains with various resistance phenotypes: studies with human THP-1 monocytes and J774 murine macrophages. Antimicrob Agents Chemother. 2015 Sep;59(9):5747-60.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₃₄FN₇O₄

[ Molecular Weight ]:
479.54800

[ Exact Mass ]:
479.26600

[ PSA ]:
126.65000

[ LogP ]:
2.48420

[ Storage condition ]:
2-8℃

Related Compounds

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