H-Gly-Pro-AMC · HBr

Names

[ Name ]:
H-Gly-Pro-AMC · HBr

[Synonym ]:
MFCD00056094
h-gly-pro-amc hbr
H-Gly-Pro-AMC · HBr

Biological Activity

[Description]:

Gly-Pro-AMC hydrobromide is a fluorescent dye, it can be used as a specific fluorescent substrate for detecting Dipeptidyl peptidase IV (DPP-IV) activity[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Gly-Pro-AMC hydrobromide (50 µM; 20 min; 37 °C) can be used as a specific fluorescent substrate for detecting DPP-IV activity[1]. Gly-Pro-AMC hydrobromide have fluorescence properties, with the fluorescence detection conditions: excitation wavelength 350 nm, fluorescence emission spectrum detection 450 nm[1].

[References]

[1]. Lammi C, et al. Soybean- and Lupin-Derived Peptides Inhibit DPP-IV Activity on In Situ Human Intestinal Caco-2 Cells and Ex Vivo Human Serum. Nutrients. 2018 Aug 13;10(8):1082.

[2]. Gallego M, et al. Dipeptidyl peptidase IV inhibitory peptides generated in Spanish dry-cured ham. Meat Sci. 2014 Feb;96(2 Pt A):757-61.

Chemical & Physical Properties

[ Boiling Point ]:
653.5ºC at 760 mmHg

[ Molecular Formula ]:
C₁₇H₂₀BrN₃O₄

[ Molecular Weight ]:
410.26200

[ Flash Point ]:
349ºC

[ Exact Mass ]:
409.06400

[ PSA ]:
105.64000

[ LogP ]:
2.65890

[ Vapour Pressure ]:
1.56E-17mmHg at 25°C

[ Storage condition ]:
−20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Fluorescence assay of x-prolyl dipeptidyl-aminopeptidase activity with a new fluorogenic substrate.

Biochem. Med. 19 , 351, (1978)