Icariside F2

Names

[ Name ]:
Icariside F2

[Synonym ]:
(2R,3R,4S,5S,6R)-2-Benzyloxy-6-((2R,3R,4S)-3,4-dihydroxy-4-hydroxymethyl-tetrahydro-furan-2-yloxymethyl)-tetrahydro-pyran-3,4,5-triol

Biological Activity

[Description]:

Icariside F2 is a potent NF-κB inhibitor with an IC50 value of 16.25 μM. Icariside F2 is an aromatic glycoside isolated from the leaves of E. ulmoides Oliver. Icariside F2 has anti-inflammatory activity[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[Target]

NF-κB:16.25 μM (IC50)

[In Vitro]

At a concentration of 10 μΜ, Icariside F2 shows little or no cytotoxic activity by the MTT assay[1].

[References]

[1]. Meng-Meng Bai, et al. Soluble epoxide hydrolase inhibitory and anti-inflammatory components from the leaves of Eucommia ulmoides Oliver (duzhong). J Agric Food Chem. 2015 Mar 4;63(8):2198-205.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₂₆O₁₀

[ Molecular Weight ]:
402.39300

[ Exact Mass ]:
402.15300

[ PSA ]:
158.30000

Related Compounds

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