Regaloside A

Names

[ Name ]:
Regaloside A

[Synonym ]:
Regaloside A

Biological Activity

[Description]:

Regaloside A, a phenylpropanoid, shows significant DPPH radical scavenging activity of 58.0% at 160 ppm. Regaloside A has anti-inflammatory activity[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> NO Synthase

Research Areas >> Inflammation/Immunology

[Target]

p65

[In Vitro]

Regaloside A (50 μg/mL; 2 hours) inhibits the expression of iNOS to 70.3 decreasing COX-2 expression to 131.6 in Raw 264.7 cells treated with LPS (1 μg/ml; pretreatment for 15 min). Regaloside A decreases the ratio of p-p65/p-65 to 40.7[1]. Regaloside A (50 μg/mL; pretreatment for 2 hours) decreases the expression of VCAM-1 to 48.6 in HASMCs with TNF-a (10 ng/ml; for 12 h)[1].

[References]

[1]. Nhan Nguyen Thi, et al. Phenylpropanoids from Lilium Asiatic hybrid flowers and their anti-inflammatory activities. Appl Biol Chem (2017) 60(5):527–533.

Chemical & Physical Properties

[ Density]:
1.51g/cm3

[ Boiling Point ]:
729.1ºC at 760mmHg

[ Molecular Formula ]:
C₁₈H₂₄O₁₀

[ Molecular Weight ]:
400.37700

[ Flash Point ]:
260.7ºC

[ Exact Mass ]:
400.13700

[ PSA ]:
166.14000

[ Vapour Pressure ]:
2.58E-22mmHg at 25°C

[ Index of Refraction ]:
1.635

[ Storage condition ]:
-20℃

Precursor & DownStream

Precursor

DownStream

Related Compounds

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