3,5-Di-tert-butylphenol

Names

[ Name ]:
3,5-Di-tert-butylphenol

[Synonym ]:
3,5-Bis(2-methyl-2-propanyl)phenol
3,5-Di-tert-butylphenol
3,5-ditert-butylphenol
MFCD00008829
Phenol, 3,5-bis(1,1-dimethylethyl)-
EINECS 214-513-4

Biological Activity

[Description]:

3,5-Di-tert-butylphenol is an volatile organic compound with anti-biofilm and antifungal activities. 3,5-Di-tert-butylphenol induces accumulation of reactive oxygen species (ROS).

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

[References]

[1]. Janarthanam Rathna, et al. Anti-biofilm mechanisms of 3,5-di-tert-butylphenol against clinically relevant fungal pathogens. Biofouling. 2016 Oct;32(9):979-93.

[2]. Jian-Hua Chen, et al. Characterization of Volatile Organic Compounds Emitted from Endophytic Burkholderia cenocepacia ETR-B22 by SPME-GC-MS and Their Inhibitory Activity against Various Plant Fungal Pathogens. Molecules. 2020 Aug 19;25(17):3765.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
276.7±9.0 °C at 760 mmHg

[ Melting Point ]:
87-89 °C(lit.)

[ Molecular Formula ]:
C₁₄H₂₂O

[ Molecular Weight ]:
206.324

[ Flash Point ]:
127.2±7.2 °C

[ Exact Mass ]:
206.167068

[ PSA ]:
20.23000

[ LogP ]:
4.86

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.499

[ Stability ]:
Stable. Incompatible with bases, acid chlorides, acid anhydrides, oxidizing agents, brass, steel, copper, copper alloys.

Safety Information

[ Hazard Codes ]:
C: Corrosive;

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
3077

[ Packaging Group ]:
III

[ Hazard Class ]:
9

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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